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Semaglutide / Cagrilintide

metabolic-research

Research Use Only

Semaglutide / Cagrilintide

5.0 · 1 review
Metabolic OptimizationSynergistic Appetite ControlWeight Management

A bundle of Semaglutide and Cagrilintide reference compounds for combined research investigation of GLP-1 receptor and amylin/calcitonin-receptor pathways. Sold for laboratory research and identification purposes only. Not for human consumption.

Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.

$189One-time

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1

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Semaglutide / Cagrilintide

$189

Technical Data

Specifications

Specifications

Technical Details

01
Purity99%+ (HPLC, each component)
02
FormLyophilized Powder
03
StorageStore at -20°C lyophilized. Reconstituted: 2–8°C, use within 28 days.
04
DosageSemaglutide 2.4 mg + Cagrilintide 2.4 mg per week in clinical research protocols
05
FormatCo-lyophilized blend
06
SourceSynthetic (both components)
07
Half-Life~7 days (each component)
08
MechanismDual GLP-1 receptor + amylin receptor agonist
09
Semaglutide MW4113.58 Da
10
Cagrilintide MW~3.9 kDa
11
Semaglutide CAS910463-68-2
12
Cagrilintide CAS2196070-45-4

Quality Assurance

Certificate of Analysis

Certificate of Analysis

COA documentation is being prepared for this product.

Contact research@roehn.co for batch-specific testing data.

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Reviews

5.0

1 verified review

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1
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1 review

Jun 2026

Fast delivery and excellent quality

I have already made four purchases on this site and couldn't be happier. The products arrived in just 2-3 days, all perfectly sealed and in great condition. Everything was exactly as described. I will definitely keep coming back!

Elias Correa Goulart· US Verified

Research Overview

About Semaglutide / Cagrilintide

Semaglutide / Cagrilintide pairs the established GLP-1 receptor agonist semaglutide with cagrilintide, a long-acting acylated analogue of the pancreatic hormone amylin. This combination exploits two mechanistically distinct but convergent pathways governing energy homeostasis — an approach grounded in the physiological observation that GLP-1 and amylin activate separate but overlapping neuronal populations within the area postrema and nucleus tractus solitarius of the hindbrain.

Amylin, co-secreted with insulin from pancreatic beta cells in response to nutrient intake, signals through calcitonin receptors complexed with receptor activity-modifying proteins (RAMPs) to slow gastric emptying, suppress post-prandial glucagon secretion, and reduce meal size through central satiety signaling. Cagrilintide's structural modifications — fatty acid acylation enabling albumin binding — extend its half-life to support once-weekly dosing while preserving the native signaling profile.

The dual GLP-1/amylin agonism framework addresses a limitation of mono-receptor approaches: compensatory upregulation of alternative appetite-stimulating pathways. By engaging both incretin and amylin receptor systems simultaneously, this combination has demonstrated additive weight reduction effects in clinical research exceeding those observed with either agent administered independently. ROEHN supplies this formulation at 99% HPLC-verified purity as a lyophilized powder, supporting translational research into next-generation multi-receptor metabolic pharmacology.