Jun 2026
Highly recommend
Highly recommend!
Courtney Yates· US Verified
metabolic-research
Research Use OnlySemaglutide
4.5 · 2 reviewsAppetite ReshapingGlucose RegulationMetabolic EfficiencyWeight Loss
Semaglutide is a synthetic 31-amino-acid peptide analogue of human GLP-1 with fatty-acid acylation extending its plasma half-life. Characterized in pre-clinical and clinical literature as a GLP-1 receptor agonist acting on incretin signaling pathways. Sold for laboratory research and identification purposes only. Not for human consumption.
Research Use Only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
$213One-time
Quantity
1
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Semaglutide
$213
Technical Data
Specifications
Specifications
Technical Details
01
Purity99%+ (HPLC)
02
FormLyophilized Powder
03
StorageStore at -20°C lyophilized. Reconstituted: 2–8°C, use within 28 days.
04
Dosage0.25–2.4 mg per week in clinical research; preclinical dosing varies by model
05
FormatLyophilized
06
SourceSynthetic
07
Half-Life~7 days
08
MechanismGLP-1 receptor agonist
09
CAS Number910463-68-2
10
Amino Acids31
11
Molecular Weight4113.58 Da
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Molecular FormulaC₁₈₇H₂₉₁N₄₅O₅₉
Quality Assurance
Certificate of Analysis
Certificate of Analysis
Batch05132025@5
PurityUSP Compliant (Endotoxin + Sterility PASS)
Test Date2025-05-19
LabPharmetric Laboratory (Largo, FL)
Verified Feedback
Reviews
4.5
2 verified reviews
5★
1
4★
1
3★
0
2★
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1★
0
2 reviews
Mar 2026
Customer service is helpful
There was an issue with shipping the correct products but they made it right. I will be happy to continue working with this company moving forward.
Trista Mann· US Verified
Research Overview
About Semaglutide
Semaglutide is a 31-amino-acid synthetic analogue of human glucagon-like peptide-1 (GLP-1) incorporating a C18 fatty diacid chain conjugated at lysine-34 via a mini-PEG linker. This structural modification confers albumin binding in plasma, resistance to DPP-4 enzymatic degradation, and a pharmacological half-life approaching seven days — enabling once-weekly dosing in clinical research protocols.
The compound acts through GLP-1 receptors distributed across the pancreatic islets, hypothalamic appetite centers, brainstem nuclei, and gastrointestinal tract. Receptor activation drives glucose-dependent insulin secretion, glucagon suppression, delayed gastric emptying, and centrally mediated appetite reduction. Clinical research programs have documented meaningful reductions in body weight attributable primarily to decreased caloric intake.
Beyond metabolic endpoints, emerging research is investigating GLP-1 receptor activation for potential cardioprotective and neuroprotective properties. ROEHN provides semaglutide at 99% HPLC-verified purity as a lyophilized powder, supporting the full spectrum of metabolic disease research from preclinical pharmacology through translational studies.
